Managing side effects involves combining lifestyle adjustments, regular monitoring and open communication with your doctor.
What is Mounjaro?
Mounjaro is a weekly prescription injection containing tirzepatide, which is a dual action medication. It belongs to the family of GLP-1 receptor agonists and Mounjaro works by increasing insulin and reducing sugar from the liver, helping lower blood sugar.
Mounjaro is approved for weight loss and weight management in adults. The medication helps by controlling appetite, enhancing feelings of fullness, reducing hunger, and curbing cravings. It is designed to be used in combination with a reduced-calorie diet and increased physical activity to support weight loss.
Side effects of Mounjaro
Any medication comes with certain side effects, understanding these side effects helps us to manage them accordingly.
Common side effects
The common side effects reported as nausea and vomiting, diarrhea, decreased appetite, constipation and abdominal pain. In a study of 2500 participants, around 80% of them reported experiencing mild to moderate side effects as listed above. Other less common side effects would be bloating, gas, mild increase in heart rate and sometimes decreased appetite.
Serious side effects
There are infrequent but severe side effects which have been reported including acute pancreatitis and gallbladder disease. Hypoglycemia (low blood sugar) and severe episodes of diarrhea can lead to dehydration and which can create kidney problems.
Tirzepatide is contraindicated in patients with a personal or family history of patients with multiple endocrine neoplasia syndrome type 2 (MEN). The medication comes with a warning regarding a potential risk of thyroid tumors, although this observation was solely made in animal trials.
How to manage the side effects of Mounjaro?
Gastrointestinal issues
Nausea is one of the most commonly reported side effects of Mounjaro. It can be managed by:
- Injecting the medicine with food to reduce stomach irritation.
- Eat smaller, frequent meals rather than large meals.
- Avoid rich, spicy or fatty foods that may aggravate nausea.
- Eating ginger, or having ginger tea/supplements may also help alleviate nausea.
- For vomiting, follow the same guidelines.
Diarrhoea occurs as the body adjusts to the medication:
- Stay hydrated by drinking plenty of water or electrolytes.
- Avoid high-fiber foods, dairy and caffeine which can worsen diarrhoea.
- Consider medicines like over the counter Imodium.
Appetite
A decreased appetite, though beneficial for weight loss can lead to reduced nutrient intake.
- A well balanced diet with sufficient vitamins and minerals.
- Consult a dietitian if you find it challenging to maintain a nutritious diet.
Injection site
There is redness, itching or swelling at the injection may occur.
- The injection site must be rotated to avoid irritating the same area.
- A cold compress to the area before and after the injection.
- A proper technique can minimise irritation.
Hypoglycemia (Low Blood Sugar)
It is not common to get low blood sugar, but when combined with other diabetic medications it can occur.
- Individuals should regularly monitor blood sugar levels.
- Carry a source of fast acting glucose to treat low blood sugars.
Fatigue
Individuals may experience tiredness and fatigue.
- Please ensure you get adequate rest and sleep.
- Incorporate light physical activity, such as walking to help boost energy levels.
- Monitor the diet to ensure a well balanced diet to have adequate energy.
General tips for managing side effects
Communicate with your regular doctor and report any side effects. This will help adjust the dosage and provide alternative treatments. Do not discontinue Mounjaro without consulting your healthcare team even if side effects are bothersome. Improper dosage routine can exacerbate side effects or reduce the treatment effectiveness.
Individuals should incorporate a healthy diet and perform regular exercise to improve overall health and manage side effects. Side effects such as fatigue or gastrointestinal issues can be managed by stress management techniques such as yoga or mindfulness. Individuals who may experience other side effects or with increased severity should consult with their doctor.
